X-ray and VUV Interaction with Biomolecules in Gas Phase (XiBiGP) Workshop

The 4th workshop on X-ray and VUV Interaction with Biomolecules in Gas Phase – XiBiGP will be co-organized with the Synchrotron SOLEIL (France) in the frame of the 31st Summer School and International Symposium on the Physics of Ionized Gases (SPIG). The XiBiGP workshop is principally related (but not exclusively) to the Section 1 of the SPIG topics.
The 4th XiBiGP workshop was originally planned for 2020: spig2020.ipb.ac.rs/XiBiGP.html but has been postponed due to the COVID pandemics.

There has been a large interest to study biological systems by using synchrotron-based spectroscopic techniques, such as Photon electron spectroscopy (PES), Photoelectron photoion coincidence spectroscopy (PEPICO), Near-edge X-ray absorption fine structure (NEXAFS), X-ray photoelectron (XPS), X-ray emission spectroscopies etc. Particularly, gas-phase spectroscopy gives the opportunity to investigate isolated targets, under well-defined conditions. However, there has been always a challenge both to bring a large biomolecule intact into the gas phase and to obtain a high-enough sensitivity for a fine structure (and even coincidence) spectroscopy of desired species in a diluted environment. It is even more challenging to investigate solvation effects under well-defined conditions.

The aim of the XiBiGP workshop is to present the most recent cutting-edge techniques used to investigate X-ray and VUV interaction with biomolecules in gas phase. The workshop is dominantly dedicated to young scientists, but also to all SPIG participants who might find interesting possibilities and topics regarding the multidisciplinary studies and developments of new experimental techniques. Finally, the aim of the workshop is to initiate a discussion between experts in the field on X-ray and VUV spectroscopy that could lead to further improvement of the techniques and important results.

The 4th XiBiGP workshop will be dedicated to PES and PEPICO investigation of small biologically relevant molecules isolated in the gas phase, bio-functionalized nanoparticles and clusters, biomolecules in liquids (in vacuo liquid jet spectroscopy) and action spectroscopy of macromolecular ions.


Dr. Aleksandar Milosavljević

Dr. Christophe Nicolas

Synchrotron SOLEIL,
Saint-Aubin - BP 48,


Synchrotron SOLEIL
L'Orme des Merisiers Saint-Aubin
BP 48 91192 Gif-sur-Yvette Cedex

RoentDek, Handels GmbH
SPECS Surface Nano Analysis GmbH

Program of the workshop (PDF)


Topical Reviews

  • Ilko Bald (University of Potsdam, Germany), Plasmon-induced chemical reactions on noble metal nanoparticles studied by synchrotron XPS and surface-enhanced Raman scattering (Section 2)
  • Thomas Schlathölter (University of Groningen, Netherlands), VUV and soft X-ray interactions with trapped biomolecular ions (Section 3)
  • Bernd Winter (Fritz Haber Institute of the Max Planck Society, Germany) An overview on the recent liquid-jet PES developments (Section 4)

Progress Reports
  • Bratislav Marinković (Institute of Physics Belgrade, Serbia), European Synchrotron and FEL User Organisation: Current Challenges and Prospects (COST Actions)

  • Section 1 - Small biologically relevant molecules

  • Michele di Fraia (Elettra-Sincrotrone Trieste, Italy), Ultrafast dynamics of photo-excited molecules at FERMI Free Electron Laser
  • Lara Martínez-Fernandez (Universidad Autónoma de Madrid, Spain), UV-induced processes in DNA
  • Laura Carlini (CNR-ISM, Italy), The ‘LEGO bricks’ of life: a gas-phase study of dipeptides
  • Marta Berholts (Tartu University, Estonia), Photofragmentation of the radiation therapy enhancers: can we make better ones?

  • Section 2 - Clusters and bio-functionalized nanoparticles

  • Jelena Pajović (University of Belgrade, Serbia), Valence band structure of isolated biomolecule-functionalized gold nanoparticles
  • Sebastian Hartweg (Synchrotron SOLEIL, France), Determination of the Adenine-Thymine binding energy
  • Darío Barreiro-Lage (Universidad Autónoma de Madrid, Spain), In the search of peptide prebiotic building blocks: Studying the fragmentation of photoionized Diketopiperazines

  • Section 3 - Isolated biomolecular ions

  • Yoni Toker (Bar Ilan University, Israel), Covalent bond formation within clusters: a pathway for the synthesis of complex molecules in the interstellar medium
  • Kaja Schubert (DESY, Germany), Isolated metalloporphyrins: Revealing their electronic structure and orbital-specific deexcitation processes experimentally
  • Aleksandar Milosavljevic (Synchrotron SOLEIL, France), X-ray absorption spectroscopy and mass spectrometry of protonated ATP molecule

  • Section 4 - Biomolecules in liquids – liquid jet spectroscopy

  • Alexandra Mocellin (Instituto de Física, Brasil), Surface propensity of small organic biomolecules in vapour-water interface by XPS
  • Jean Philippe Renault (University Paris Saclay, France), Electronic structure and solvation effects from core and valence photoelectron spectroscopy of serum albumin
  • Jerome Palaudoux (Sorbonne University, France), First (e,e) coincidence measurements at PLEIADES beamline on solvated benzoate in water using a new magnetic bottle time-of-flight spectrometer


June 9 2022
Deadline for contributed papers and abstracts is extended to 17.6.

Feb 9 2022
First Announcement

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